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Correspondence
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Volume 333:1286-1287 November 9, 1995 Number 19
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Childhood Leukemias

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 by Pui, C.-H.
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To the Editor: The successful treatment of leukemia is one of the great triumphs of modern pediatrics. Twenty-five years ago, a diagnosis of childhood leukemia was a virtual death sentence. Today, as lucidly described by Pui (June 15 issue),1 the majority of children with leukemia are cured.

Unfortunately, the incidence of childhood leukemia has not declined. Instead, the incidence rate for new cases has increased steadily in the United States over the past two decades. For acute lymphoblastic leukemia (ALL), the most common form of leukemia among children, the cumulative increase in the incidence rate from 1973 to 1991 was . . . [Full Text of this Article]

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