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Previous Volume 333:1423-1424 November 23, 1995 Number 21 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: In a large cohort study, Sánchez-Guerrero et al. (June 22 issue)¹ found no association between silicone breast implants and connective-tissue diseases, defined according to a variety of standardized criteria, or signs and symptoms of these diseases. The study provides further strong evidence that the case definition for silicone-related disorders does not include systemic lupus erythematosus or rheumatoid arthritis. It has been recognized since 1992, however, that most symptomatic women with breast implants have a chronic fatigue and fibromyalgia-like syndrome.^2,3,4 It is unclear why the authors excluded the very syndrome in which they should have been the most . . . [Full Text of this Article]

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