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Previous Volume 333:1475-1484 November 30, 1995 Number 22 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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A variety of skin diseases, autoimmune and inherited, are characterized by the presence of blisters. In some, such as pemphigus vulgaris, blistering is the primary manifestation. In others, such as lichen planus, blisters are infrequent. Most of these diseases are associated with substantial morbidity; a few may result in death. Although the general approach to the treatment of these diseases is similar, the diagnosis of the specific disease is important, because the most appropriate dosage and timing of some commonly used medications vary considerably. This review covers the management of the major acquired bullous diseases; diseases only rarely associated with . . . [Full Text of this Article]

Autoimmune Bullous Diseases

Systemic Corticosteroid Therapy

Topical Corticosteroid Therapy

Other Immunosuppressive Drugs

Dapsone and Related Drugs

Chrysotherapy

Plasmapheresis

Dietary Interventions

Other Therapies

Erythema Multiforme and Stevens–Johnson Syndrome

Systemic Corticosteroid Therapy

Other Immunosuppressive Drugs

Acyclovir and Erythema Multiforme

Other Therapeutic Options

Toxic Epidermal Necrolysis

General Principles of Treatment

Systemic Corticosteroid Therapy

Conclusions

Source Information

From the Departments of Dermatology and Epidemiology, University of North Carolina at Chapel Hill; and the National Epidermolysis Bullosa Registry — both in Chapel Hill, N.C.

Address reprint requests to Dr. Fine at the Department of Dermatology, University of North Carolina at Chapel Hill, Suite 3100, Thurston Bldg., CB# 7287, Chapel Hill, NC 27599.

References

Related Letters:

Management of Acquired Bullous Skin Diseases
Guibal F., Roujeau J.-C., Stern R. S., Weissel M., Fine J.-D.
Extract | Full Text  
N Engl J Med 1996; 334:864-865, Mar 28, 1996. Correspondence

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