Ischemic stroke may occur with sudden cruelty and, when notfatal, may deplete the resources of the patient, family, andcommunity. The most effective treatments are directed at theunderlying causes of the initial ischemic event, the preventionof recurrence, and the reduction of potential risk factors,but they do little for the stroke itself. The majority of ischemicstrokes, roughly 80 percent, result from thromboembolic or atherothromboticprocesses. This underscores the fact that stroke is a vasculardisorder with neurologic consequences, and provides a basisfor the use of antithrombotic agents as therapy. The idea ofusing plasminogen activators . . . [Full Text of this Article]
References
Related Letters:
Tissue Plasminogen Activator for Acute Ischemic Stroke
Friedman H. S., Koroshetz W. J., The Massachusetts General Hospital Stroke Service , Qureshi N., Marler J. R., The NINDS-PA Stroke Study Group , del Zoppo G. J.
Extract |
Full Text
N Engl J Med 1996;
334:1405-1406, May 23, 1996.
Correspondence
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