Patients with rheumatoid arthritis have symmetric synovitisof their peripheral joints and various degrees of joint destruction.In short-term studies, slow-acting antirheumatic drugs relievesymptoms and retard joint destruction, but many patients continueto have pain, stiffness, fatigue, and progressive disability.1Better treatments are needed. This issue of the Journal includesreports of two randomized, controlled trials that investigatedvariations of widely used treatments for rheumatoid arthritis.2,3
In a six-month study of 148 patients with severe rheumatoidarthritis who had had only partial improvement with methotrexate,Tugwell et al. found greater clinical improvement with cyclosporineand methotrexate combined than with . . . [Full Text of this Article]
References
This article has been cited by other articles:
Lindegaard, H, Vallo, J, Horslev-Petersen, K, Junker, P, Ostergaard, M
(2001). Low field dedicated magnetic resonance imaging in untreated rheumatoid arthritis of recent onset. Ann Rheum Dis
60: 770-776
[Abstract][Full Text]