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Original Article
Brief Report
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Volume 333:294-296 August 3, 1995 Number 5
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Treatment of a Laboratory-Acquired Sabiá Virus Infection
Michele Barry, M.D., Mark Russi, M.D., M.P.H., Lori Armstrong, Ph.D., David Geller, M.D., Ph.D., Robert Tesh, M.D., Louise Dembry, M.D., Jean Paul Gonzalez, M.D., Ali S. Khan, M.D., and Clarence J. Peters, M.D.

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Arenaviruses are a group of RNA viruses several of which have the potential to cause a deadly syndrome of hemorrhagic fever. In humans these viruses are usually transmitted by exposure to infected rodent excreta; occasional laboratory or nosocomial infections have been reported.1 Sabiá virus is an arenavirus that was first isolated in São Paulo, Brazil, in 1990 from an agricultural engineer who presented with a hemorrhagic fever syndrome and ultimately died. Necrosis of the liver was found at autopsy. The virus was subsequently characterized as a new member of the Tacaribe complex of the family Arenaviridae.2 A laboratory technician in . . . [Full Text of this Article]

Case Report

Occupational Exposure

Case Presentation and Clinical Course

Biosafety Management and Contact Surveillance

Discussion


Source Information

From the Department of Internal Medicine (M.B., M.R., D.G., L.D.) and Yale Arbovirus Research Unit, Department of Epidemiology and Public Health (R.T.), Yale University School of Medicine, New Haven, Conn.; the Special Pathogens Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta (L.A., A.S.K., C.J.P.); and Institut Français de Recherche Scientifique pour le Développement en Coopération, Paris (J.P.G.).

Address reprint requests to Dr. Barry at the International Health Program, Yale University School of Medicine, 20 York St., New Haven, CT 06504.

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