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Previous Volume 333:298-303 August 3, 1995 Number 5 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Heterosexual transmission is responsible for most infection with the human immunodeficiency virus (HIV). The increase in pediatric HIV infection has had a substantial impact on childhood mortality, both in industrialized countries, such as the United States,¹ and in developing countries.² In some areas in sub-Saharan Africa, 10 to 30 percent of pregnant women are HIV-infected, and infection is now spreading to parts of Southeast Asia.

Reporting of pediatric cases of the acquired immunodeficiency syndrome (AIDS) to public health authorities, registers of HIV-infected children, and unlinked anonymous testing of antenatal and neonatal blood samples make it possible to monitor the prevalence . . . [Full Text of this Article]

Antenatal HIV Testing

Vertical Transmission

Risk Factors for Transmission

Viral Characteristics

Neutralizing Antibody

Pregnancy and Delivery

Breast-Feeding

Diagnosis of HIV Infection

Timing of Vertical Transmission

Natural History

Treatment of Infants

Prophylaxis against P. carinii Pneumonia

Protection against Other Infections

Reduction of Vertical Transmission

Antiretroviral Therapy

Other Approaches

Conclusions

Source Information

From the Institute of Child Health and the Great Ormond Street Hospital for Children, London.

Address reprint requests to Dr. Peckham at the Department of Epidemiology and Biostatistics, Institute of Child Health, 30 Guilford St., London WC1, United Kingdom.

References

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