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Previous Volume 333:315-317 August 3, 1995 Number 5 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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During the development of the human embryo, hematopoietic cells first appear in the yolk sac, then migrate to the liver and from there to the bone marrow through the bloodstream. Until the 1970s, it was assumed that these cells resided exclusively in the bone marrow, but then hematopoietic cells capable of mitosis were identified in the blood of laboratory animals and humans.^1,2 Before that, all normal blood cells were considered to be terminally differentiated, moving to the circulation only after they had completed a series of maturational mitoses in the marrow. Investigators wondered whether these newly found mitotic blood cells . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Engelhardt, M., Bertz, H., Afting, M., Waller, C. F., Finke, J. (1999). High- Versus Standard-Dose Filgrastim (rhG-CSF) for Mobilization of Peripheral-Blood Progenitor Cells From Allogeneic Donors and CD34+ Immunoselection. JCO 17: 2160-2160 [Abstract] [Full Text]  
• Juliusson, G., Brugger, W., Kanz, L. (1996). Hematopoietic Reconstitution with Autologous Stem Cells. NEJM 334: 271-272 [Full Text]