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Previous Volume 333:321-322 August 3, 1995 Number 5 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: We wish to address a statement made by Dr. Wong in his discussion of the differential diagnosis of panhypogammaglobulinemia in the Case Records (March 9 issue).¹ Dr. Wong states that "adults with HIV [human immunodeficiency virus]-associated diseases typically present with elevated or normal immunoglobulin levels, whereas diminished levels are observed in children with HIV infection." In our experience, the vast majority of children with symptomatic or asymptomatic HIV infection have hypergammaglobulinemia. By six months of age, almost all HIV-infected children have serum immunoglobulin concentrations at least 2 SD higher than the age-adjusted mean,² and hypergammaglobulinemia may be . . . [Full Text of this Article]

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