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Previous Volume 334:800-801 March 21, 1996 Number 12 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article by Marcus, A. J. Related Article by Giovannucci, E.

To the Editor: The report by Giovannucci et al. (Sept. 7 issue)¹ documenting a chemopreventive effect of aspirin against the development of colorectal cancer in women adds evidence to the already abundant data strongly suggesting that nonsteroidal antiinflammatory drugs (NSAIDs) have antineoplastic effects in the colon. Recent findings, however, call into question the hypothesis that these authors and Marcus² in his accompanying editorial suggest — that the antineoplastic effect of NSAIDs is mediated mainly by their ability to inhibit the synthesis of prostaglandins.

As Giovannucci et al. note, NSAIDs cause regression of colonic polyps and desmoid tumors in patients with . . . [Full Text of this Article]

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