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Previous Volume 334:835-840 March 28, 1996 Number 13 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Since 1948, when the World Health Organization defined health as being not only the absence of disease and infirmity but also the presence of physical, mental, and social well-being,¹ quality-of-life issues have become steadily more important in health care practice and research. There has been a nearly exponential increase in the use of quality-of-life evaluation as a technique of clinical research since 1973, when only 5 articles listed "quality of life" as a reference key word in the MEDLINE data base; during the subsequent five-year periods, there were 195, 273, 490, and 1252 such articles. The growing fields of outcomes . . . [Full Text of this Article]

Conceptualizing Quality-of-Life Outcomes

Measuring Quality of Life

Constructing Scales of Measurement

Coverage

Reliability

Validity

Responsiveness

Sensitivity

Evaluating Quality of Life in Health Research

Analytic Models of Health — The Role of Quality-of-Life Assessment

Selecting an Assessment Instrument

Interpreting Quality-of-Life Effects

The Need for Practical Clinical Applications

Source Information

From the Department of Biostatistics, Harvard School of Public Health (M.A.T.); and the Department of Medicine, Joslin Diabetes Center, Brigham and Women's Hospital, and Harvard Medical School (D.C.S.) — all in Boston.

Address reprint requests to Dr. Testa at the Department of Biostatistics, Harvard School of Public Health, 677 Huntington Ave., Boston, MA 02115.

References

Related Letters:

Assessment of Quality of Life
Buchholz W. M., Bradlyn A. S., Pollock B. H., Meran J. G., Testa M. A., Simonson D. C.
Extract | Full Text  
N Engl J Med 1996; 335:520-522, Aug 15, 1996. Correspondence

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