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Previous Volume 334:857-858 March 28, 1996 Number 13 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The first complete description of transient hypothyroxinemia in low-birth-weight infants dates from 1981,¹ and there has since been much speculation about the causes of the phenomenon. The hypothyroxinemia may be caused by a special type of nonthyroidal illness, although an association with the severity of prenatal or postnatal illness has never been demonstrated, by a metabolic adaptation of the preterm infant to extrauterine life, especially to the impaired oxygenation caused by the respiratory distress syndrome, or by incomplete maturation of the hypothalamic–pituitary–thyroid axis. This transient hypothyroxinemia is seldom called hypothyroidism, because most authors believe that thyroxine therapy is not justified. . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Chan, S., Kachilele, S., Hobbs, E., Bulmer, J. N., Boelaert, K., McCabe, C. J., Driver, P. M., Bradwell, A. R., Kester, M., Visser, T. J., Franklyn, J. A., Kilby, M. D. (2003). Placental Iodothyronine Deiodinase Expression in Normal and Growth-Restricted Human Pregnancies. J. Clin. Endocrinol. Metab. 88: 4488-4495 [Abstract] [Full Text]  
• van Wassenaer, A. G., Kok, J. H. (2000). Thyroid Function and Thyroid Hormone Requirements of Very Preterm Infants. NeoReviews 1: e116-121 [Full Text]  
• Kilby, M. D., Verhaeg, J., Gittoes, N., Somerset, D. A., Clark, P. M. S., Franklyn, J. A. (1998). Circulating Thyroid Hormone Concentrations and Placental Thyroid Hormone Receptor Expression in Normal Human Pregnancy and Pregnancy Complicated by Intrauterine Growth Restriction (IUGR). J. Clin. Endocrinol. Metab. 83: 2964-2971 [Abstract] [Full Text]  
• Smit, B. J., Kok, J. H., de Vries, L. S., van Wassenaer, A. G., Dekker, F. W., Ongerboer de Visser, B. W. (1998). Somatosensory Evoked Potentials in Very Preterm Infants in Relation to L-Thyroxine Supplementation. Pediatrics 101: 865-869 [Abstract] [Full Text]  
• (1996). HYPOTHYROXINEMIA: ANOTHER PROBLEM FOR PREMATURE INFANTS?. JWatch General 1996: 5-5 [Full Text]