Autoimmune hepatitis is a chronic necroinflammatory liver disorderof unknown cause associated with circulating autoantibodiesand a high serum globulin level. Since the first descriptionsof the disorder in the 1950s, it has been known by a varietyof terms, most commonly "autoimmune chronic active hepatitis,"but in 1992 the International Autoimmune Hepatitis Group recommendedthe term "autoimmune hepatitis" as the most appropriate andleast redundant for this disease.1 It is important to distinguishautoimmune hepatitis from other forms of liver disease becausea high percentage of cases respond to antiinflammatory and immunosuppressivetreatment. Early diagnosis with appropriate management can . . . [Full Text of this Article]
Pathological Features
Pathogenesis
Clinical Features and Diagnosis
Treatment
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From the Gastroenterology Unit, University of Vermont College of Medicine, Burlington.
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