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Previous Volume 334:922-923 April 4, 1996 Number 14 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Roujeau et al. (Dec. 14 issue)¹ present data showing a morbidity of 1 in 230,000 associated with toxic epidermic necrolysis and the Stevens–Johnson syndrome due to one week of trimethoprim–sulfamethoxazole therapy. If the death rate is assumed to be 15 percent,² the mortality rate would be 1 in 1,550,000. It would be interesting to know the actual mortality among their index patients.

To put this excess mortality in context, it is similar to the transfusion-associated frequency of human immunodeficiency virus transmission in Germany (1 in 800,000 to 1 in 2,000,000)^3,4 and the United States (1 in 450,000 . . . [Full Text of this Article]

References

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