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Volume 334:989 April 11, 1996 Number 15
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Radiotherapy and Surgery in Early Breast Cancer

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 by Early Breast Cancer Trialists' Collaborative Group
To the Editor: I wish to propose some alternative ways to group patients and trials in the analysis of radiotherapy and surgery in early breast cancer, reported by the Early Breast Cancer Trialists' Collaborative Group (Nov. 30 issue).1

The studies included in Figure 1 and Figure 3 of the article used widely varying surgical and radiotherapeutic techniques. In a prior overview, single-agent and multiagent chemotherapeutic regimens and different periods of tamoxifen therapy were found to have different effects.2 Therefore, both absolute rates of local and regional recurrence and the proportional reductions with the more extensive treatment should be listed for . . . [Full Text of this Article]

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