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Review Article
Drug Therapy
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Volume 334:1178-1184 May 2, 1996 Number 18
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Antiparasitic Drugs
Leo X. Liu, M.D., D.T.M.H., and Peter F. Weller, M.D.

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Infections with parasitic helminths and protozoa are important causes of morbidity and mortality worldwide. Chemotherapy has an important role not only in the treatment of individual patients but also, in conjunction with public health and vector-control measures, in reducing the transmission of parasitic infections. At present, however, there are no vaccines for human parasitic infections, the scientific knowledge necessary to develop antiparasitic drugs is rudimentary, and the mechanisms of action of most antiparasitic drugs are poorly understood. Commercial incentives for the production of drugs designed to fight infections that are mainly endemic in developing countries are limited, and some proved . . . [Full Text of this Article]

Anthelmintic Drugs

Albendazole

            Echinococcosis

            Intestinal Tapeworms and Cysticercosis

            Intestinal Roundworms

            Other Roundworms

Ivermectin

            Onchocerciasis

            Other Filariases

            Other Roundworms

            Ectoparasites

Praziquantel

            Schistosomiasis

            Other Flukes

            Cestodes

Antiprotozoal Drugs

Albendazole

            Giardiasis

            Microsporidiosis

Fumagillin

            Ocular Microsporidiosis

Trimethoprim–Sulfamethoxazole

            Cyclosporiasis

            Isosporiasis

Paromomycin

            Cryptosporidiosis

Conclusions


Source Information

From the Department of Medicine, Harvard Medical School, and the Infectious Diseases Division, Beth Israel Hospital — both in Boston.

Address reprint requests to Dr. Weller at Beth Israel Hospital, DA-617, 330 Brookline Ave., Boston, MA 02215.

References


Related Letters:

Percutaneous Drainage of Hydatid Cysts
Schipper H. G., Kager P. A., Vasen W., Filice C., Brunetti E., Khuroo M. S.
Extract | Full Text  
N Engl J Med 1998; 338:391-393, Feb 5, 1998. Correspondence

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