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Previous Volume 334:1200-1201 May 2, 1996 Number 18 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: In his editorial (Jan. 18 issue),¹ Dr. Collins discusses many of the issues surrounding the presymptomatic testing of women for BRCA1 mutations when their families are at high risk for breast and ovarian cancer. Because of the high frequency of the 185delAG mutation in Ashkenazi Jews² and because this single mutation accounts for a large proportion of hereditary cases in the population,³ we offer testing for the mutation at McGill University and the University of Toronto. We explain that only a positive test is informative and that once a positive case is identified in the family, we . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Stern, H. J., Maddalena, A., Schulman, J. D., Foulkes, W. D., Bunn, H. F., Stossel, T. P., Forget, B. G., Stamatoyannopoulos, G., Weatherall, D. J., Hubbard, R., Lewontin, R.C. (1996). Pitfalls of Genetic Testing. NEJM 335: 1235-1237 [Full Text]