FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 334:125 January 11, 1996 Number 2 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited PubMed Citation

To the Editor: Administration of praziquantel for 15 days is effective therapy for patients with parenchymal brain cysticercosis.¹ Because the plasma and cerebrospinal fluid concentrations of praziquantel are highest two hours after its administration, after which they decline rapidly,^2,3 we hypothesized that a high concentration that was maintained for about six hours by giving three doses at two-hour intervals might increase the length of time the parasite was exposed to high concentrations of drug and be sufficient cysticidal therapy for these patients. We therefore treated 10 patients (6 women and 4 men; mean [±SD] age, 33±11 years) with parenchymal brain . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Garcia, H. H., Evans, C. A. W., Nash, T. E., Takayanagui, O. M., White, A. C. Jr., Botero, D., Rajshekhar, V., Tsang, V. C. W., Schantz, P. M., Allan, J. C., Flisser, A., Correa, D., Sarti, E., Friedland, J. S., Martinez, S. M., Gonzalez, A. E., Gilman, R. H., Del Brutto, O. H. (2002). Current Consensus Guidelines for Treatment of Neurocysticercosis. Clin. Microbiol. Rev. 15: 747-756 [Abstract] [Full Text]  
• Lopez-Gomez, M., Castro, N., Jung, H., Sotelo, J., Corona, T. (2001). Optimization of the single-day praziquantel therapy for neurocysticercosis. Neurology 57: 1929-1929 [Full Text]  
• Chang, G. Y., Ko, D. Y., Hagemann, G., Witte, O. W., Gottstein, B. (2000). Isolated Echinococcus granulosus hydatid cyst in the CNS with severe reaction to treatment. Neurology 54: 778-778 [Full Text]  
• Del Brutto, O. H., Campos, X., Sanchez, J., Mosquera, A. (1999). Single-day praziquantel versus 1-week albendazole for neurocysticercosis. Neurology 52: 1079-1079 [Abstract] [Full Text]  
• Salgado, P., Rojas, R., Sotelo, J. (1997). Cysticercosis: Clinical Classification Based on Imaging Studies. Arch Intern Med 157: 1991-1997 [Abstract]