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Editorial
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Volume 334:1397-1399 May 23, 1996 Number 21
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The Changing Approach to the Treatment of Early Breast Cancer

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For decades, the order of the therapeutic steps in early-stage, invasive breast cancer was largely unchallenged, proceeding according to the widely accepted priorities of Halsted with their emphasis on local tumor control: "curative" mastectomy was followed by adjuvant radiotherapy and then by everything else — if there was anything else. This established approach was challenged 20 years ago by the increased use of adjuvant systemic therapy for early breast cancer. The benefits of adjuvant systemic therapy and the evident inability of postoperative radiation to the chest wall to prolong survival rendered the use of adjuvant radiotherapy after modified radical or . . . [Full Text of this Article]

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