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Correspondence
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Volume 334:1547-1548 June 6, 1996 Number 23
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Acellular Pertussis Vaccines

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 by Edwards, K. M.
To the Editor: As a participating observer at the International Symposium on Pertussis Vaccine Trials, I was surprised to read the following statement in the editorial by Edwards and Decker (Feb. 8 issue)1: "All the acellular vaccines evaluated in the six studies that included a whole-cell vaccine had absolute efficacies that approached or exceeded those of their comparison whole-cell vaccine."

Table 1 shows the relevant data from these studies. On the basis of these data, a different conclusion can easily be drawn. In four of the six trials, the efficacy of the whole-cell vaccine exceeded that of the acellular . . . [Full Text of this Article]

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