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Correspondence
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Volume 334:1549 June 6, 1996 Number 23
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Hepatitis GB Virus C in Patients on Hemodialysis

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To the Editor: A new group of Flaviviridae viruses — hepatitis GB virus C (HGBV-C)1 and hepatitis G virus (HGV)2 — has recently been described. Patients infected with these viruses have persistent viremia, and they may have chronic hepatitis.

We tested the serum of 61 patients on hemodialysis for HGBV-C, using a reverse-transcriptase–nested polymerase-chain-reaction (PCR) method with primers located in the NS3 region of the viral genome. The outer primers1 were GB-C-a1 and GB-C-sl, and the inner primers were GBCSMAR (sense, 5'ATCCCCTTTTATGGGCATGG) and GBCAMAR (antisense, 5'GARCTGTCYTTiCCCCTRTAATA, in which R denotes A or G and Y denotes C or T). There . . . [Full Text of this Article]

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