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Previous Volume 334:1642-1648 June 20, 1996 Number 25 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Hyperbaric oxygen — 100 percent oxygen at two to three times the atmospheric pressure at sea level — can result in arterial oxygen tension in excess of 2000 mm Hg¹ and oxygen tension in tissue of almost 400 mm Hg.^2,3 Such doses of oxygen have a number of beneficial biochemical, cellular, and physiologic effects, and today there are 259 hyperbaric facilities in the United States with 344 single-occupant ("monoplace") hyperbaric-oxygen chambers.⁴ In this article, we review the mechanisms of action, evidence of clinical efficacy, and risks of therapy with hyperbaric oxygen.

Physiologic Effects

For hyperbaric oxygen, pressure is expressed in multiples of . . . [Full Text of this Article]

Biochemical and Cellular Effects

Administration

Therapeutic Uses of Hyperbaric Oxygen

Carbon Monoxide Poisoning

Decompression Sickness

Arterial Gas Embolism

Radiation-Induced Tissue Injury

Clostridial Myonecrosis

Necrotizing Fasciitis

Refractory Osteomyelitis

Acute Traumatic Ischemic Injury

Compromised Skin Grafts and Flaps

Anemia Due to Exceptional Blood Loss

Thermal Burns

Problem Wounds

Adverse Effects

Cost

Conclusions

Source Information

From the Department of Emergency Medicine, University of Massachusetts Medical Center, 55 Lake Ave. N., Worcester, MA 01655, where reprint requests should be addressed to Dr. Tibbles.

References

Related Letters:

Hyperbaric-Oxygen Therapy
Geiderman J. M., Ault M. J., Jain K.K., Schaefer B., Weinstock V. M., Weinstock S. J., Tibbles P. M., Edelsberg J. S.
Extract | Full Text  
N Engl J Med 1996; 335:1684-1686, Nov 28, 1996. Correspondence

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