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Images in Clinical Medicine
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Volume 335:26 July 4, 1996 Number 1
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Tropheryma Whippelii

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Figure 1A.




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Figure 1. A 46-year-old man presented with a 50-lb (23-kg) weight loss and diarrhea. An electron micrograph (Panel A, x6913) of tissue from the small bowel showed numerous extracellular bacilli (Tropheryma whippelii; A), a phagosome containing bacilli (B) within a macrophage (M), and a neutrophil (N). Staining of the tissue with hematoxylin and eosin (Panel B, x10) revealed clubbed epithelial villi (E) and foamy macrophages (FM). Periodic acid–Schiff staining (Panel C, x40) showed clubbed villi, lipid droplets, and lamina propria packed with positive-staining macrophages.

 
Figure 1B.

Figure 1C.


Edward J. Fricker, M.D.
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