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Previous Volume 335:750-751 September 5, 1996 Number 10 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Kuipers et al. (April 18 issue)¹ describe an increased risk of atrophic gastritis, associated with an increased risk of gastric cancer,² in patients with reflux esophagitis and Helicobacter pylori infection who are treated with omeprazole. A recent consensus statement from the National Institutes of Health (NIH) recommended using antimicrobial therapy in addition to an antisecretory agent only in H. pylori–infected patients who have peptic ulcers.³ Kuipers et al. suggest that treating H. pylori–infected patients with proton-pump inhibitors alone, whether they have ulcers or not, may increase the risk of atrophic gastritis and, consequently, of gastric . . . [Full Text of this Article]

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