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Correspondence
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Volume 335:753 September 5, 1996 Number 10
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Autoimmune Hepatitis

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To the Editor: In Dr. Krawitt's excellent review of autoimmune hepatitis (April 4 issue),1 he discusses the importance of distinguishing autoimmune hepatitis from acute viral hepatitis. In the differential diagnosis, he mentions hepatitis A, B, C, and E and infection with Epstein–Barr virus, cytomegalovirus, and herpes simplex viruses, but he neglects to mention acute primary infection with the human immunodeficiency virus (HIV).

Elevated aminotransferase concentrations have been reported in 21 percent of patients with symptomatic primary HIV infection,2 and an acute-hepatitis–like picture has been described.3 The benefits of an early diagnosis of acute HIV infection include the potential for early . . . [Full Text of this Article]

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