Malaria is the world's most important parasitic infection. Althoughit has been eradicated from temperate zones, increasing numbersof travelers from temperate areas each year visit tropical countries,where the disease remains a major cause of morbidity and death.The treatment of malaria has changed over the past two decadesin response to declining drug sensitivity in Plasmodium falciparumand a resurgence of the disease in tropical areas. This reviewwill concentrate on the practical aspects of treatment.
Diagnosis
Patients with malaria usually present with nonspecific and irregularfever, chills, headache, and malaise. Vomiting occurs in approximately20 percent of patients, . . . [Full Text of this Article]
Uncomplicated Malaria
Children and Pregnant Women
Severe P. falciparum Malaria
Management
Treatment
Chloroquine
Quinine and Quinidine
Artemisinin
Ancillary Treatment
The Future
Source Information
From the Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; the Wellcome Trust Clinical Research Unit, Centre for Tropical Diseases, Cho Quan Hospital, Ho Chi Minh City, Vietnam; and the Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Headington, Oxford, United Kingdom.
Address reprint requests to Prof. White at the Faculty of Tropical Medicine, 420/6 Rajvithi Rd., Mahidol University, Bangkok 10400, Thailand.
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