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Review Article
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Volume 335:800-806 September 12, 1996 Number 11
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The Treatment of Malaria
N.J. White, D.Sc., M.D.

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Malaria is the world's most important parasitic infection. Although it has been eradicated from temperate zones, increasing numbers of travelers from temperate areas each year visit tropical countries, where the disease remains a major cause of morbidity and death. The treatment of malaria has changed over the past two decades in response to declining drug sensitivity in Plasmodium falciparum and a resurgence of the disease in tropical areas. This review will concentrate on the practical aspects of treatment.

Diagnosis

Patients with malaria usually present with nonspecific and irregular fever, chills, headache, and malaise. Vomiting occurs in approximately 20 percent of patients, . . . [Full Text of this Article]

Uncomplicated Malaria

Children and Pregnant Women

Severe P. falciparum Malaria

Management

Treatment

            Chloroquine

            Quinine and Quinidine

            Artemisinin

            Ancillary Treatment

The Future


Source Information

From the Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; the Wellcome Trust Clinical Research Unit, Centre for Tropical Diseases, Cho Quan Hospital, Ho Chi Minh City, Vietnam; and the Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Headington, Oxford, United Kingdom.

Address reprint requests to Prof. White at the Faculty of Tropical Medicine, 420/6 Rajvithi Rd., Mahidol University, Bangkok 10400, Thailand.

References


Related Letters:

The Treatment of Malaria
Bailey C. L., White N. J.
Extract | Full Text  
N Engl J Med 1997; 336:733-734, Mar 6, 1997. Correspondence

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