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Correspondence
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Volume 335:1239-1240 October 17, 1996 Number 16
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More on Pravastatin and Coronary Disease

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To the Editor: In a recent letter to the editor (May 16 issue),1 Rogers raised questions about the cost effectiveness of treatment of hypercholesterolemia. His calculations were derived from the West of Scotland Coronary Prevention Study.2 I propose that a more sober account of cost effectiveness is in order. There are three major issues concerning the use of cholesterol-lowering drugs to prevent coronary heart disease: efficacy, safety, and cost effectiveness. A recent cost analysis of the use of 3-hydroxy-3-methylglutaryl–coenzyme A reductase inhibitors (statins) in secondary prevention indicated a high degree of cost effectiveness.3 Costs were much lower than for many . . . [Full Text of this Article]

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Related Letters:

Prevention of Coronary Heart Disease with Pravastatin
Rogers S., Samani N. J., de Bono D. P., Davis D. R., Shepherd J., Cobbe S. M., Ford I., The West of Scotland Coronary Prevention Study Group , Pedersen T. R.
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N Engl J Med 1996; 334:1333-1335, May 16, 1996. Correspondence

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