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Previous Volume 335:1320-1322 October 24, 1996 Number 17 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: In the clear and critical review of acute renal failure by Thadhani et al. (May 30 issue),¹ the authors summarize the management issues and at present "do not recommend the routine use of dopamine for either prophylaxis or treatment of established acute renal failure." Our experience, however, suggests that a randomized, controlled study is long overdue. Dopamine and furosemide are highly synergistic in maintaining the glomerular filtration rate in early nephrotoxic acute tubular necrosis in dogs.² Neither drug is as effective by itself. Furthermore, a frequently cited clinical study³ and an editorial in the Lancet ⁴ inappropriately conclude . . . [Full Text of this Article]

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