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Previous Volume 335:1322-1323 October 24, 1996 Number 17 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: With regard to the report by Taha et al. (May 30 issue)¹ on the effect of famotidine in preventing endoscopically diagnosed gastric and duodenal ulcers, it is important to distinguish between endoscopic lesions induced by nonsteroidal antiinflammatory drugs (NSAIDs) and NSAID-induced serious gastrointestinal complications such as bleeding and perforation. The former are common, and depending on how they are defined, can be seen in up to 80 percent of patients treated with NSAIDs.² Among the 389 patients screened by Taha et al., 104 (27 percent) had an endoscopic ulcer and were therefore excluded from the trial. Over . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Graham, D. Y., Agrawal, N. M., Campbell, D. R., Haber, M. M., Collis, C., Lukasik, N. L., Huang, B. (2002). Ulcer Prevention in Long-term Users of Nonsteroidal Anti-inflammatory Drugs: Results of a Double-blind, Randomized, Multicenter, Active- and Placebo-Controlled Study of Misoprostol vs Lansoprazole. Arch Intern Med 162: 169-175 [Abstract] [Full Text]