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Previous Volume 335:1660-1668 November 28, 1996 Number 22 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Despite improvement in primary prevention¹ and treatment,² acute myocardial infarction remains the chief cause of death in the United States and most developed countries. Almost half of all victims of myocardial infarction die before they reach the hospital.³ Of several hundred thousand patients hospitalized each year with acute myocardial infarction, 7 to 15 percent die during hospitalization and another 7 to 15 percent die during the following year.⁴

This article reviews the current evidence from published randomized trials (Table 1) and meta-analyses (Table 2) of adjunctive drug therapy with beta-adrenergic antagonists, angiotensin-converting–enzyme (ACE) inhibitors, nitrates, calcium-channel . . . [Full Text of this Article]

Beta-Adrenergic–Antagonist Drugs

ACE Inhibitors

Nitrates

Calcium-Channel Blockers

Antiarrhythmic Drugs

Magnesium

Conclusions

Source Information

From the Division of Preventive Medicine (C.H.H., C.M.A., S.L.G., J.M.G., J.E.B.) and the Cardiovascular Division (J.M.G.), Department of Medicine, Brigham and Women's Hospital; the Cardiovascular Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School (C.M.A.); the Department of Ambulatory Care and Prevention, Harvard Medical School (C.H.H., J.E.B.); the Department of Epidemiology, Harvard School of Public Health (C.H.H., J.E.B.); and the Department of Medicine, Brockton–West Roxbury Veterans Affairs Medical Center (J.M.G.) — all in Boston.

Address reprint requests to Dr. Hennekens at the Division of Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Ave. East, Boston, MA 02215-1204.

References

Related Letters:

Adjunctive Drug Therapy for Acute Myocardial Infarction
Bostom A. G., Bhargava M., Sharma A., de Tena J. G., Hennekens C. H., Albert C. M., Buring J. E.
Extract | Full Text  
N Engl J Med 1997; 336:1455-1456, May 15, 1997. Correspondence

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