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Correspondence
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Volume 335:209 July 18, 1996 Number 3
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Herpes Simplex Encephalitis

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 by Watemberg, N.
To the Editor: Drs. Watemberg and Morton (March 7 issue) describe a case of herpes simplex encephalitis in a 13-year-old boy and present the classic electroencephalographic finding of periodic lateralized epileptiform discharges.1 Whereas it is gratifying to learn that the boy recovered fully after treatment with 15 mg of acyclovir per kilogram of body weight per day for 14 days, the only studies that have prospectively evaluated intravenous acyclovir for the treatment of herpes simplex encephalitis have used a dosage of 30 mg per kilogram per day (10 mg per kilogram every 8 hours) for 10 days.2,3 This standard dose . . . [Full Text of this Article]

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