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Editorial
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Volume 335:586-587 August 22, 1996 Number 8
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Treatment of Benign Prostatic Hyperplasia

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Medications to treat benign prostatic hyperplasia fall into two main categories: {alpha}1-adrenergic–antagonist drugs, which relax smooth muscle in the prostate, and drugs that inhibit 5{alpha}-reductase, which shrink the prostate by blocking the formation of the chief intracellular androgen, dihydrotestosterone.1 The main question is, Which drug is better, or would a combination of the two work best? In this issue of the Journal, Lepor et al. report the results of a landmark study by the Veterans Affairs Cooperative Studies Benign Prostatic Hyperplasia Study Group that attempts to answer this question.2

The authors found that treatment with terazosin, an {alpha}1-adrenergic antagonist, . . . [Full Text of this Article]

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