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Previous Volume 336:870-871 March 20, 1997 Number 12 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Acute tubular necrosis is common in acutely ill hospitalized patients, with mortality rates exceeding 50 percent.¹ The regenerative capacity of kidneys damaged by acute tubular necrosis is substantial, and minimizing renal injury or accelerating renal recovery may therefore have a substantial effect on patients' survival. Accordingly, identifying new therapeutic approaches to alter the natural history of the disease and reduce morbidity and mortality is a pressing challenge.²

In this issue of the Journal, Allgren et al. report the results of a prospective study of anaritide, a 25-amino-acid synthetic form of atrial natriuretic peptide, in patients with acute tubular necrosis.³ The . . . [Full Text of this Article]

References

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• Haussler, U., von Wichert, G., Schmid, R. M., Keller, F., Schneider, G. (2005). Epidermal growth factor activates nuclear factor-{kappa}B in human proximal tubule cells. Am. J. Physiol. Renal Physiol. 289: F808-F815 [Abstract] [Full Text]  
• Gruberg, L., Mintz, G. S., Mehran, R., Dangas, G., Lansky, A. J., Kent, K. M., Pichard, A. D., Satler, L. F., Leon, M. B. (2000). The prognostic implications of further renal function deterioration within 48 h of interventional coronary procedures in patients with pre-existent chronic renal insufficiency. J Am Coll Cardiol 36: 1542-1548 [Abstract] [Full Text]