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Previous Volume 336:1014-1016 April 3, 1997 Number 14 Next

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Cardiac and cerebral ischemic events develop unpredictably in patients with widely varying degrees of atherosclerotic disease. Thus, a major area of research is the study of the stimuli that provoke ischemic events. The weak relation between ischemic events and flow-limiting stenoses in the coronary and carotid arteries leaves room for innovative research.¹ However, it is easier to study the details of accepted paradigms than it is to develop new hypotheses, just as it was easier to map the visible face of the moon than it was to explore its hidden side.

The study by Ridker et al. in this issue . . . [Full Text of this Article]

References

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• Hussain, T., Burch, M., Fenton, M. J., Whitmore, P. M., Rees, P., Elliott, M., Aurora, P. (2007). Positive Pretransplantation Cytomegalovirus Serology Is a Risk Factor for Cardiac Allograft Vasculopathy in Children. Circulation 115: 1798-1805 [Abstract] [Full Text]  
• Yates, R. B., Stafford-Smith, M. (2006). The genetic determinants of renal impairment following cardiac surgery.. SEMIN CARDIOTHORAC VASC ANESTH 10: 314-326 [Abstract]  
• Li, J.-J., Fang, C.-H., Qian, H.-Y., Hu, W.-L. (2006). Time Course of Rapid C-Reactive Protein Reduction by Pravastatin in Patients with Stable Angina. ANGIOLOGY 57: 1-7 [Abstract]  
• Li, J.-J., Fang, C.-H. (2005). Effects of 4 Weeks of Atorvastatin Administration on the Antiinflammatory Cytokine Interleukin-10 in Patients with Unstable Angina. Clin. Chem. 51: 1735-1738 [Full Text]  
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• Di Napoli, P, Taccardi, A A, Barsotti, A (2005). Long term cardioprotective action of trimetazidine and potential effect on the inflammatory process in patients with ischaemic dilated cardiomyopathy. Heart 91: 161-165 [Abstract] [Full Text]  
• Leon, A. S., Franklin, B. A., Costa, F., Balady, G. J., Berra, K. A., Stewart, K. J., Thompson, P. D., Williams, M. A., Lauer, M. S. (2005). Cardiac Rehabilitation and Secondary Prevention of Coronary Heart Disease: An American Heart Association Scientific Statement From the Council on Clinical Cardiology (Subcommittee on Exercise, Cardiac Rehabilitation, and Prevention) and the Council on Nutrition, Physical Activity, and Metabolism (Subcommittee on Physical Activity), in Collaboration With the American Association of Cardiovascular and Pulmonary Rehabilitation. Circulation 111: 369-376 [Abstract] [Full Text]  
• Grau, A. J., Boddy, A. W., Dukovic, D. A., Buggle, F., Lichy, C., Brandt, T., Hacke, W., for the CAPRIE Investigators, (2004). Leukocyte Count as an Independent Predictor of Recurrent Ischemic Events. Stroke 35: 1147-1152 [Abstract] [Full Text]  
• Wakatsuki, A., Ikenoue, N., Shinohara, K., Watanabe, K., Fukaya, T. (2004). Effect of Lower Dosage of Oral Conjugated Equine Estrogen on Inflammatory Markers and Endothelial Function in Healthy Postmenopausal Women. Arterioscler. Thromb. Vasc. Bio. 24: 571-576 [Abstract] [Full Text]  
• Marroquin, O. C., Kip, K. E., Kelley, D. E., Johnson, B. D., Shaw, L. J., Bairey Merz, C. N., Sharaf, B. L., Pepine, C. J., Sopko, G., Reis, S. E., for the Women's Ischemia Syndrome Evaluation Inves, (2004). Metabolic Syndrome Modifies the Cardiovascular Risk Associated With Angiographic Coronary Artery Disease in Women: A Report From the Women's Ischemia Syndrome Evaluation. Circulation 109: 714-721 [Abstract] [Full Text]  
• Johnson, B. D., Kip, K. E., Marroquin, O. C., Ridker, P. M, Kelsey, S. F., Shaw, L. J., Pepine, C. J., Sharaf, B., Bairey Merz, C. N., Sopko, G., Olson, M. B., Reis, S. E. (2004). Serum Amyloid A as a Predictor of Coronary Artery Disease and Cardiovascular Outcome in Women: The National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE). Circulation 109: 726-732 [Abstract] [Full Text]  
• Anzai, T., Yoshikawa, T., Kaneko, H., Maekawa, Y., Iwanaga, S., Asakura, Y., Ogawa, S. (2004). Association Between Serum C-Reactive Protein Elevation and Left Ventricular Thrombus Formation After First Anterior Myocardial Infarction. Chest 125: 384-389 [Abstract] [Full Text]  
• Tousoulis, D, Davies, G, Stefanadis, C, Toutouzas, P, Ambrose, J A (2003). Inflammatory and thrombotic mechanisms in coronary atherosclerosis. Heart 89: 993-997 [Abstract] [Full Text]  
• Huang, M., Pang, X., Karalis, K., Theoharides, T. C. (2003). Stress-induced interleukin-6 release in mice is mast cell-dependent and more pronounced in Apolipoprotein E knockout mice. Cardiovasc Res 59: 241-249 [Abstract] [Full Text]  
• Vlachoyiannopoulos, P. G., Kanellopoulos, P. G., Ioannidis, J. P. A., Tektonidou, M. G., Mastorakou, I., Moutsopoulos, H. M. (2003). Atherosclerosis in premenopausal women with antiphospholipid syndrome and systemic lupus erythematosus: a controlled study. Rheumatology (Oxford) 42: 645-651 [Abstract] [Full Text]  
• Chanard, J., Lavaud, S., Randoux, C., Rieu, P. (2003). New insights in dialysis membrane biocompatibility: relevance of adsorption properties and heparin binding. Nephrol Dial Transplant 18: 252-257 [Full Text]  
• Kurth, T., Gaziano, J. M., Berger, K., Kase, C. S., Rexrode, K. M., Cook, N. R., Buring, J. E., Manson, J. E. (2002). Body Mass Index and the Risk of Stroke in Men. Arch Intern Med 162: 2557-2562 [Abstract] [Full Text]  
• Ikeda, U., Maeda, Y., Yamamoto, K., Shimada, K. (2002). C-Reactive protein augments inducible nitric oxide synthase expression in cytokine-stimulated cardiac myocytes. Cardiovasc Res 56: 86-92 [Abstract] [Full Text]  
• Altman, R., Luciardi, H. L., Muntaner, J., Del Rio, F., Berman, S. G., Lopez, R., Gonzalez, C. (2002). Efficacy Assessment of Meloxicam, a Preferential Cyclooxygenase-2 Inhibitor, in Acute Coronary Syndromes Without ST-Segment Elevation: The Nonsteroidal Anti-Inflammatory Drugs in Unstable Angina Treatment-2 (NUT-2) Pilot Study. Circulation 106: 191-195 [Abstract] [Full Text]  
• Rifai, N., Buring, J. E., Lee, I-M., Manson, J. E., Ridker, P. M (2002). Is C-Reactive Protein Specific for Vascular Disease in Women?. ANN INTERN MED 136: 529-533 [Abstract] [Full Text]  
• Glurich, I., Grossi, S., Albini, B., Ho, A., Shah, R., Zeid, M., Baumann, H., Genco, R. J., De Nardin, E. (2002). Systemic Inflammation in Cardiovascular and Periodontal Disease: Comparative Study. CVI 9: 425-432 [Abstract] [Full Text]  
• Maseri, A., Cianflone, D. (2002). Inflammation in acute coronary syndromes. Eur Heart J Suppl 4: B8-B13 [Abstract]  
• Mallat, Z., Corbaz, A., Scoazec, A., Besnard, S., Leseche, G., Chvatchko, Y., Tedgui, A. (2001). Expression of Interleukin-18 in Human Atherosclerotic Plaques and Relation to Plaque Instability. Circulation 104: 1598-1603 [Abstract] [Full Text]  
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• Berton, G, Cordiano, R, Palmieri, R, Cucchini, F, de Toni, R, Palatini, P (2001). Microalbuminuria during acute myocardial infarction; a strong predictor for 1-year mortality. Eur Heart J 22: 1466-1475 [Abstract]  
• Valen, G., Yan, Z.-q., Hansson, G.o. K. (2001). Nuclear factor kappa-B and the heart. J Am Coll Cardiol 38: 307-314 [Abstract] [Full Text]  
• Best, P.J.M., Gersh, B.J. (2001). Cell adhesion molecules and inflammation in acute coronary syndromes: markers and emerging risk factors. Eur Heart J 22: 1155-1159  
• O'malley, T, Ludlam, C.A, Riemermsa, R.A, Fox, K.A.A (2001). Early increase in levels of soluble inter-cellular adhesion molecule-1 (sICAM-1). Potential risk factor for the acute coronary syndromes. Eur Heart J 22: 1226-1234 [Abstract]  
• Hansson, G.K. (2001). The stabilized plaque: will the dream come true?. Eur Heart J Suppl 3: C69-C75  
• Katritsis, D., Korovesis, S., Giazitzoglou, E., Parissis, J., Kalivas, P., Webb-Peploe, M. M., Ioannidis, J. P.A., Haliassos, A. (2001). C-Reactive Protein Concentrations and Angiographic Characteristics of Coronary Lesions. Clin. Chem. 47: 882-886 [Abstract] [Full Text]  
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• Pasceri, V., Willerson, J. T., Yeh, E. T. H. (2000). Direct Proinflammatory Effect of C-Reactive Protein on Human Endothelial Cells. Circulation 102: 2165-2168 [Abstract] [Full Text]  
• Muhlestein, J. B., Horne, B. D., Carlquist, J. F., Madsen, T. E., Bair, T. L., Pearson, R. R., Anderson, J. L. (2000). Cytomegalovirus Seropositivity and C-Reactive Protein Have Independent and Combined Predictive Value for Mortality in Patients With Angiographically Demonstrated Coronary Artery Disease. Circulation 102: 1917-1923 [Abstract] [Full Text]  
• Hingorani, A. D., Cross, J., Kharbanda, R. K., Mullen, M. J., Bhagat, K., Taylor, M., Donald, A. E., Palacios, M., Griffin, G. E., Deanfield, J. E., MacAllister, R. J., Vallance, P. (2000). Acute Systemic Inflammation Impairs Endothelium-Dependent Dilatation in Humans. Circulation 102: 994-999 [Abstract] [Full Text]  
• Brunet, P., Berland, Y. (2000). Water quality and complications of haemodialysis. Nephrol Dial Transplant 15: 578-580 [Full Text]  
• Ridker, P. M., Hennekens, C. H., Buring, J. E., Rifai, N. (2000). C-Reactive Protein and Other Markers of Inflammation in the Prediction of Cardiovascular Disease in Women. NEJM 342: 836-843 [Abstract] [Full Text]  
• Wierzbicki, A. (2000). Lipids, cardiovascular disease and atherosclerosis in systemic lupus erythematosus. Lupus 9: 194-201 [Abstract]  
• Morrow, D. A., Rifai, N., Antman, E. M., Weiner, D. L., McCabe, C. H., Cannon, C. P., Braunwald, E. (2000). Serum amyloid A predicts early mortality in acute coronary syndromes: a TIMI 11A substudy. J Am Coll Cardiol 35: 358-362 [Abstract] [Full Text]  
• Maresca, G., Di Blasio, A., Marchioli, R., Di Minno, G. (1999). Measuring Plasma Fibrinogen to Predict Stroke and Myocardial Infarction : An Update. Arterioscler. Thromb. Vasc. Bio. 19: 1368-1377 [Abstract] [Full Text]  
• Liuzzo, G., Buffon, A., Biasucci, L. M., Gallimore, J. R., Caligiuri, G., Vitelli, A., Altamura, S., Ciliberto, G., Rebuzzi, A. G., Crea, F., Pepys, M. B., Maseri, A. (1998). Enhanced Inflammatory Response to Coronary Angioplasty in Patients With Severe Unstable Angina. Circulation 98: 2370-2376 [Abstract] [Full Text]  
• Kalayoglu, M. V., Byrne, G. I. (1998). A Chlamydia pneumoniae Component That Induces Macrophage Foam Cell Formation Is Chlamydial Lipopolysaccharide. Infect. Immun. 66: 5067-5072 [Abstract] [Full Text]  
• Caligiuri, G., Liuzzo, G., Biasucci, L. M., Maseri, A. (1998). Immune system activation follows inflammation in unstable angina: pathogenetic implications. J Am Coll Cardiol 32: 1295-1304 [Abstract] [Full Text]  
• Corseaux, D., Le Tourneau, T., Six, I., Ezekowitz, M. D., Mc Fadden, E. P., Meurice, T., Asseman, P., Bauters, C., Jude, B. (1998). Enhanced Monocyte Tissue Factor Response After Experimental Balloon Angioplasty in Hypercholesterolemic Rabbit: Inhibition With Dietary L-Arginine. Circulation 98: 1776-1782 [Abstract] [Full Text]  
• Christenson, R. H., Azzazy, H. M. E. (1998). Biochemical markers of the acute coronary syndromes. Clin. Chem. 44: 1855-1864 [Abstract] [Full Text]  
• Anderson, J. L., Carlquist, J. F., Muhlestein, J. B., Horne, B. D., Elmer, S. P. (1998). Evaluation of C-reactive protein, an inflammatory marker, and infectious serology as risk factors for coronary artery disease and myocardial infarction. J Am Coll Cardiol 32: 35-41 [Abstract] [Full Text]  
• van der Wal, A C, Piek, J J, de Boer, O J, Koch, K T, Teeling, P, van der Loos, C M, Becker, A E (1998). Recent activation of the plaque immune response in coronary lesions underlying acute coronary syndromes. Heart 80: 14-18 [Abstract] [Full Text]  
• Skolbekken, J. A. (1998). Communicating the risk reduction achieved by cholesterol reducing drugs. BMJ 316: 1956-1958 [Full Text]  
• Pasceri, V., Cammarota, G., Patti, G., Cuoco, L., Gasbarrini, A., Grillo, R. L., Fedeli, G., Gasbarrini, G., Maseri, A. (1998). Association of Virulent Helicobacter pylori Strains With Ischemic Heart Disease. Circulation 97: 1675-1679 [Abstract] [Full Text]  
• Walkup, J., Satriano, J., Hansell, S., Olfson, M. (1998). Practices Related to HIV Risk Assessment in General Hospital Psychiatric Units in New York State. Psychiatr. Serv. 49: 529-530 [Abstract] [Full Text]  
• Weitzman, M. (1998). The Pure Pleasure of the Process: Reflections of a General Pediatric Researcher. Pediatrics 101: 304-305 [Full Text]  
• Muller, J. E., Kaufmann, P. G., Luepker, R. V., Weisfeldt, M. L., Deedwania, P. C., Willerson, J. T. (1997). Mechanisms Precipitating Acute Cardiac Events : Review and Recommendations of an NHLBI Workshop. Circulation 96: 3233-3239 [Full Text]  
• Gambino, R. (1997). C-Reactive Protein—Undervalued, Underutilized. Clin. Chem. 43: 2017-2018 [Full Text]  
• Murray, W. M., Bruno, J. J., Cahill, M. R., Perry, I. J., Rus, H., Niculescu, F. I., Ridker, P. M., Hennekens, C. H., Maseri, A. (1997). Inflammation, Aspirin, and the Risk of Cardiovascular Disease. NEJM 337: 422-424 [Full Text]  
• Wakatsuki, A., Okatani, Y., Ikenoue, N., Fukaya, T. (2002). Effect of Medroxyprogesterone Acetate on Vascular Inflammatory Markers in Postmenopausal Women Receiving Estrogen. Circulation 105: 1436-1439 [Abstract] [Full Text]  
• Heeschen, C., Hamm, C. W., Laufs, U., Snapinn, S., Bohm, M., White, H. D. (2002). Withdrawal of Statins Increases Event Rates in Patients With Acute Coronary Syndromes. Circulation 105: 1446-1452 [Abstract] [Full Text]