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Correspondence
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Volume 336:1026-1027 April 3, 1997 Number 14
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Premature Atherosclerosis in Familial Chylomicronemia

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 by Benlian, P.
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To the Editor: Benlian et al. (Sept. 19 issue)1 describe four patients with familial chylomicronemia due to lipoprotein lipase deficiency and, contrary to current opinion,2 conclude that such patients have an increased risk of premature atherosclerosis. Both Patients 1 and 2 were women who had angina after the age of 50 years and whose coronary angiograms showed severe stenosis. However, one of them was a smoker and the other had non-insulin–dependent diabetes mellitus, since she had received oral hypoglycemic agents. Patient 3 was a 52-year-old man free of cardiovascular symptoms, with a normal exercise-tolerance test. Patient 4 was a heavy . . . [Full Text of this Article]

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