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Figure 1. A 32-year-old man infected with the human immunodeficiency virus presented with multiple papules of various sizes, many of which were umbilicated. The lesions were located mainly on his face (Panel A), with lesser involvement of the trunk, buttocks, arms, and legs. A Tzanck preparation of the gelatinous core obtained by curettage from one of the papules revealed encapsulated yeast forms (Panel B; Wright's stain, x400). This simple technique permitted a rapid presumptive diagnosis of Cryptococcus neoformans. Subsequent cultures of cerebrospinal fluid, blood, and skin grew C. neoformans. After the patient received a total dose of 1500 . . . [Full Text of this Article] |
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