Among health care workers who have occupational exposures tothe human immunodeficiency virus (HIV), a recent case–controlstudy indicates that treatment with zidovudine after exposuredecreases the odds of HIV infection by 79 percent.1 Althoughthis observation has not been confirmed in a randomized, controlledtrial, antiretroviral treatment is now the standard of carein the event of a parenteral occupational exposure to HIV.2,3,4The probability of HIV infection due to puncture by a contaminatedneedle is similar to that estimated for a single episode ofunprotected receptive anal or vaginal intercourse with an infectedpartner or for a single . . . [Full Text of this Article]
Risks Associated with Sexual and Injection-Drug Exposures
The Efficacy and Safety of Postexposure Treatment
Risks Associated with Postexposure Treatment
Recommendations for Treatment
Toward a Public Health Policy
Conclusions
Address reprint requests to Dr. Katz at the AIDS Office, 25 Van Ness Ave., Suite 500, San Francisco, CA 94102-6033.
References
Related Letters:
Postexposure Treatment of HIV
Li R. W., Wong J. B., Pinkerton S. D., Holtgrave D. R., Bloom F. R., Katz M. H., Gerberding J. L.
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N Engl J Med 1997;
337:499-501, Aug 14, 1997.
Correspondence
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