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Correspondence
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Volume 336:1105-1107 April 10, 1997 Number 15
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Adrenal Insufficiency

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 by Oelkers, W.
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To the Editor: The concise review of adrenal insufficiency by Dr. Oelkers (Oct. 17 issue)1 was excellent, but the corticotropin stimulation test is even less valuable than he suggests, and the incidence of clinically significant secondary adrenal insufficiency due to long-term glucocorticoid therapy is much lower than generally believed.2,3,4,5 What does Dr. Oelkers recommend for patients receiving exogenous glucocorticoids? My data suggest that the adrenal function of such patients need not be tested except when there are clear-cut clinical indications, since in such patients the physiologic value of the biochemical tests is poor and clinical adrenal insufficiency is rare.


Jonathan . . . [Full Text of this Article]

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