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Previous Volume 336:1244-1245 April 24, 1997 Number 17 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Historically, infants undergoing circumcision have not been given analgesia. The rationale was that infants do not feel, localize, or remember pain. In reality, they have all the anatomical and functional components required for nociception, and they react appropriately to painful stimuli.^1,2,3,4,5 During circumcision boys are agitated, cry intensely, and have changes in facial expression. Their heart rates and blood pressure increase, and their oxygenation decreases. Their serum cortisol, -endorphin, and catecholamine concentrations rise. Clearly, circumcision is painful.

In this issue of the Journal, Taddio and colleagues report the results of a study of the safety and efficacy of lidocaine–prilocaine cream . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Van Howe, R. S., Svoboda, J. S. (2008). Neonatal Pain Relief and the Helsinki Declaration. J Law Med Ethics 36: 803-823  
• Van Howe, R. S, Svoboda, J S., Hodges, F. M (2005). HIV infection and circumcision: cutting through the hyperbole. The Journal of the Royal Society for the Promotion of Health 125: 259-265 [Abstract]  
• Van Howe, R. S. (2004). A Cost-Utility Analysis of Neonatal Circumcision. Med Decis Making 24: 584-601 [Abstract]  
• Gesundheit, B., Grisaru-Soen, G., Greenberg, D., Levtzion-Korach, O., Malkin, D., Petric, M., Koren, G., Tendler, M. D., Ben-Zeev, B., Vardi, A., Dagan, R., Engelhard, D. (2004). Neonatal Genital Herpes Simplex Virus Type 1 Infection After Jewish Ritual Circumcision: Modern Medicine and Religious Tradition. Pediatrics 114: e259-e263 [Abstract] [Full Text]  
• Schoen, E. J., Colby, C. J., Ray, G. T. (2000). Newborn Circumcision Decreases Incidence and Costs of Urinary Tract Infections During the First Year of Life. Pediatrics 105: 789-793 [Abstract] [Full Text]  
• Schoen, E. J., Wiswell, T. E., Moses, S. (2000). New Policy on Circumcision---Cause for Concern. Pediatrics 105: 620-623 [Full Text]  
• Schoen, E. J., Oehrli, M., Machin, G. (2000). The Highly Protective Effect of Newborn Circumcision Against Invasive Penile Cancer. Pediatrics 105: 36e-36 [Abstract] [Full Text]  
• Van Howe;, R. S., Butler-O'Hara, M., LeMoine, C., Guillet, R. (1999). Pain Relief for Neonatal Circumcision: Serious Design Flaws?. Pediatrics 103: 196-196 [Full Text]  
• Storms, M. R., Schlesinger, Y., Urbach, J. (1998). Circumcision and Endocarditis Prophylaxis. Arch Pediatr Adolesc Med 152: 1038-1039 [Full Text]  
• Horger III, E. O., Arnett, R. M., Jones, J. S., Andersson, C., Van Howe, R. S., Cold, C. J., Shechet, J., Fried, S. M., Tanenbaum, B., Lander, J., Metcalfe, J. B., Muttitt, S., Brady-Fryer, B. (1998). Local Anesthesia for Infants Undergoing Circumcision. JAMA 279: 1169-1171 [Full Text]  
• Schlesinger, Y., Urbach, J. (1998). Circumcision and Endocarditis Prophylaxis. Arch Pediatr Adolesc Med 152: 412-412 [Full Text]