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Previous Volume 336:1314-1316 May 1, 1997 Number 18 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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With better knowledge of the genetics of various diseases, testing for the underlying defects with the use of biochemical and molecular techniques is increasingly possible. The practical aim of these tests is the prevention and treatment of disease. The first widespread screening test was for the detection of phenylketonuria in newborns. In addition to screening newborns, there are other strategies for identifying genetic disorders. Screening for fetal disease has become common during pregnancy and includes searching for chromosomal defects (such as in Down's syndrome) with amniocentesis or chorionic-villus sampling. Screening of maternal blood for alpha-fetoprotein to detect neural-tube defects and . . . [Full Text of this Article]

References

Related Letters:

Genetic Screening of Adolescents
Spiegler G. E., Motulsky A. G.
Extract | Full Text  
N Engl J Med 1997; 337:639-640, Aug 28, 1997. Correspondence

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