To the Editor: Ritonavir (Norvir, Abbott Laboratories), a proteaseinhibitor used to treat people with human immunodeficiency virus(HIV) infection, reportedly has no adverse effects on renalfunction.1,2 We describe a patient in whom acute renal failuredeveloped shortly after the start of treatment with ritonavir.
The patient was a 40-year-old man with HIV infection and stablechronic renal failure. His kidney disease was thought to bedue to a horseshoe kidney and to glomerular disease of unknowncause, manifested by an episode of proteinuria in the nephroticrange and, more recently, by the excretion of 1 to 2 g . . . [Full Text of this Article]
References
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