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Previous Volume 336:1675-1676 June 5, 1997 Number 23 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Dr. Sinaiko's review of hypertension in children (Dec. 26 issue)¹ includes a recommendation to use oral nifedipine capsules for urgent or emergency treatment of hypertension. Dr. Sinaiko states, "For rapid absorption the drug must first be removed from the capsule or the patient must bite through the capsule." The sublingual absorption of nifedipine is negligible, whereas absorption from the gastrointestinal tract is complete.² Removing the drug from the capsule is often associated with unintentional losses, such as spillage or loss from the mouth, which make the dose of the drug administered uncertain. A significant decline in blood . . . [Full Text of this Article]

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