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Correspondence
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Volume 336:1836-1837 June 19, 1997 Number 25
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Acute Pancreatitis during Primary HIV-1 Infection

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To the Editor: The most common clinical presentation of primary infection with the human immunodeficiency virus type 1 (HIV-1) is a mononucleosis-like illness.1 Other clinical manifestations include Pneumocystis carinii pneumonia,2 cryptosporidiosis,3 herpes esophagitis,4 and hemorrhagic fever.5 We describe two patients in whom symptomatic primary HIV-1 infection was associated with acute pancreatitis.

A 52-year-old heterosexual man with an HIV-1–positive partner presented with fever (38.5°C), severe abdominal pain, vomiting, and cervical and axillary lymphadenopathy. Three days later a diffuse macular rash appeared. The laboratory data are shown in Table 1. Ultrasonography and computed tomography (CT) demonstrated edema of the pancreas, with . . . [Full Text of this Article]

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