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Previous Volume 336:506-507 February 13, 1997 Number 7 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Microorganisms and other agents continually threaten the intestinal mucosa, calling for the gut to prevent damage, restore epithelium in regions in which cells are lost, and suppress inflammation. How does the intestine tackle these problems? Although cytokines deep in the lamina propria moderate immune responses and inflammatory injury, other repair factors operate on the apical side of the epithelial cells — the front line where mucosa and the outside world really interact. Since restoration of epithelial continuity occurs early in mucosal healing, agents that help reseal mucosal wounds must undoubtedly influence cell proliferation and perhaps accelerate the migration of proliferating . . . [Full Text of this Article]

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