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Correspondence
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Volume 336:585-586 February 20, 1997 Number 8
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Enoxaparin as Prophylaxis against Thromboembolism after Total Hip Replacement

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 by Bergqvist, D.
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To the Editor: We are concerned about the report of Bergqvist et al. (Sept. 5 issue)1 and the implications it may have for patient care. They reported that among patients who had total hip arthroplasty, the rate of venography-confirmed deep-vein thrombosis was substantially reduced in those who had continuing prophylaxis with the low-molecular-weight heparin enoxaparin after hospital discharge, compared with a control group that received enoxaparin prophylaxis only while hospitalized. Although we do not question the validity of these findings, we do challenge the clinical significance of the results. Venography-confirmed deep-vein thrombosis after orthopedic surgery is an excellent end point . . . [Full Text of this Article]

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