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Correspondence
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Volume 336:589-590 February 20, 1997 Number 8
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Heroin Inhalation and Progressive Spongiform Leukoencephalopathy

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To the Editor: We report two cases of a progressive spongiform leukoencephalopathy that, to our knowledge, has not been reported previously in the United States. The disease occurred after the patients inhaled heated heroin vapor, a practice known as "chasing the dragon."

In Patient 1, a 21-year-old woman with a six-month history of inhaling heroin vapor, progressive bradykinesia, ataxia, and slurred speech developed over a two-week period. She denied using intravenous drugs. On admission she had abulia. She followed simple, one-step commands, but there was a long period of latency before she initiated movements, which were slow and ataxic. She . . . [Full Text of this Article]

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