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Correction to Leach et al., N Engl J Med 335(11):761-767 September 12, 1996.

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Volume 336:660 February 27, 1997 Number 9
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Perflubron in Infants with Severe Respiratory Distress Syndrome

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 by Leach, C. L.
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 by Leach, C. L.
To the Editor: Leach et al. report (Sept. 12 issue)1 that partial liquid ventilation with perfluorocarbons in premature infants may be an effective therapy for severe respiratory distress syndrome. Their conclusion that such treatment prevented oxygen toxicity, reduced the incidence of barotrauma due to improved dynamic compliance, and improved ventilation — each of which is a highly desirable goal of therapy in neonates with this often fatal syndrome — may not be supported by the results.

Each neonate was reintubated at entry into the study, but the authors do not mention the size of the new tube and whether retained . . . [Full Text of this Article]

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