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Correspondence
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Volume 336:660-661 February 27, 1997 Number 9
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Intellectual Function of Children Exposed to Polychlorinated Biphenyls in Utero

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 by Jacobson, J. L.
To the Editor: Drs. Jacobson and Jacobson (Sept. 12 issue)1 reported that low-level exposure to polychlorinated biphenyls (PCBs) in utero is associated with lower IQ scores (by an average of 6.2 points) among school-age children. The results seem implausible given the fact that among Taiwanese children who were exposed prenatally to levels of PCBs that were 10 to 20 times higher and to levels of certain congeners of polychlorinated dibenzofurans that were 100,000 times higher than background levels, the IQ score was only 5 points lower than that in unexposed children.2

Several methodologic flaws cast doubt on the validity of . . . [Full Text of this Article]

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