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Correspondence
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Volume 336:661-662 February 27, 1997 Number 9
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Remission of Progressive Multifocal Leukoencephalopathy Following Splenectomy and Antiretroviral Therapy in a Patient with HIV Infection

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To the Editor: Progressive multifocal leukoencephalopathy caused by JC papovavirus infection of glial cells is an increasingly frequent complication of human immunodeficiency virus (HIV) type 1 infection. To date, there is no treatment available for progressive multifocal leukoencephalopathy, and it usually results in death within three to six months of diagnosis.1 We report on a 30-year-old man with hemophilia and AIDS (CD4 count, 64 cells per cubic millimeter) who was being treated with d4T and Septra and who came to our clinic with a two-week history of headache, diplopia, and left-arm ataxia. The patient had a normal mental status (HIV . . . [Full Text of this Article]

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