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Correspondence
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Volume 337:51-53 July 3, 1997 Number 1
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Venous Thromboembolism

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To the Editor: Schulman et al. (Feb. 6 issue)1 reported that long-term anticoagulant therapy may benefit patients with recurrent venous thromboembolism. Their conclusions will be difficult to interpret in a clinical setting, however, because of the heterogeneity of their study population. Twenty percent of their patients were identified as having temporary risk factors for thromboembolism. For them, removing or resolving the risk factor may substantially reduce the risk of recurrent thrombosis, independently of the anticoagulant therapy; moreover, intuitively, those patients would be expected to be the best candidates for a short course of such therapy. The failure either to exclude . . . [Full Text of this Article]

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